Dashnaiv Peptides

Calculators

Survodutide dosage calculator

Enter a vial and a dose and this returns the concentration, the volume and the syringe units. Underneath it, the same arithmetic worked out in advance for common vials, and the doses published studies of Survodutide actually used, every one quoted and cited. It converts numbers. It does not suggest what to take.

Work out concentration and what to draw

Two divisions, both shown. Concentration = mass in the vial ÷ diluent volume. Volume to draw = mass you want ÷ that concentration. Syringe units are that volume × the units per millilitre on your syringe's own scale.

Worked example: 5 mg in 2 mL is 2,500 mcg/mL, so 250 mcg is 0.1 mL, which is 10 units on a U-100 syringe and 4 units on a U-40. The scale is printed on the barrel; reading a U-40 syringe as if it were U-100 is a two-and-a-half-fold error.

Survodutide reconstitution chart

Units on a standard U-100 insulin syringe, where 100 units is 1 mL. The rows are the absolute doses quoted in studies of Survodutide, from 1.8 mg to 6 mg, so this chart is specific to this compound rather than a generic ladder. More diluent means more units for the same dose, which is easier to measure accurately and empties the vial no faster.

2 mg vial of Survodutide. Figures are units on a U-100 syringe; a cell over 100 units does not fit in one 1 mL syringe.
Dose 1 mL diluent
(2,000 mcg/mL)		2 mL diluent
(1,000 mcg/mL)		3 mL diluent
(667 mcg/mL)
1.8 mg 90180 >1 mL270 >1 mL
2.7 mg 135 >1 mL270 >1 mL405 >1 mL
3.6 mg 180 >1 mL360 >1 mL540 >1 mL
6 mg 300 >1 mL600 >1 mL900 >1 mL
5 mg vial of Survodutide. Figures are units on a U-100 syringe; a cell over 100 units does not fit in one 1 mL syringe.
Dose 1 mL diluent
(5,000 mcg/mL)		2 mL diluent
(2,500 mcg/mL)		3 mL diluent
(1,667 mcg/mL)
1.8 mg 3672108 >1 mL
2.7 mg 54108 >1 mL162 >1 mL
3.6 mg 72144 >1 mL216 >1 mL
6 mg 120 >1 mL240 >1 mL360 >1 mL
10 mg vial of Survodutide. Figures are units on a U-100 syringe; a cell over 100 units does not fit in one 1 mL syringe.
Dose 1 mL diluent
(10,000 mcg/mL)		2 mL diluent
(5,000 mcg/mL)		3 mL diluent
(3,333 mcg/mL)
1.8 mg 183654
2.7 mg 275481
3.6 mg 3672108 >1 mL
6 mg 60120 >1 mL180 >1 mL

Read a figure off this chart only if it matches the vial in front of you. A vial labelled a different strength, or reconstituted with a different volume, gives a different number for the same dose, and that is the single most common way these calculations go wrong.

Doses in published studies of Survodutide

Each row is quoted from a paper in this compound's source ledger and carries the kind of evidence it came from. 4 of 4 come from human studies; the rest are animal or laboratory work.

What studies of Survodutide administered, as published. A record of what happened, not a menu.
EvidenceDose as the paper states itSource
Human clinical trialIn SYNCHRONIZE-1, 725 adults with obesity received once-weekly survodutide titrated to 3.6 mg or 6.0 mg, or placebo, for 76 weeks.pmid-42253238
Human clinical trialIn SYNCHRONIZE-MASLD, 216 adults with obesity and at-risk liver disease received 6.0 mg weekly or placebo, two to one.pmid-42252333
Human clinical trialThe type 2 diabetes phase 2 tested 0.3 to 2.7 mg once weekly and 1.2 or 1.8 mg twice weekly for 16 weeks against placebo and open-label semaglutide.pmid-38095657
Human clinical trialThe phase 3 programme titrates to 3.6 or 6.0 mg with dose flexibility permitted.pmid-39495965

Escalation schedules used in studies

Where a trial raised the dose over time rather than starting at the target, this is what it did. The starting dose is often the part that decides tolerability, which is why it is reported here and not only the dose the trial finished on.

How long studies ran, and how far a vial goes

A vial lasts for a number of draws, not a number of weeks: divide the mass in the vial by the mass per draw and round down, which the vial planner does. How long that represents depends on frequency. For context, these are the durations studies of Survodutide actually ran for.

How Survodutide was given

The route changes what a dose means. The same number given intravenously and subcutaneously is not the same exposure.

Questions people ask

How many units is 1.8 mg of Survodutide?
It depends entirely on how the vial was reconstituted. In a 5 mg vial with 2 mL of diluent it is 72 units on a U-100 syringe; with 1 mL it is 36. The chart above gives the rest.
Does adding more diluent waste the peptide?
No. The mass in the vial does not change. More diluent spreads the same mass through more liquid, so each dose is a larger, easier-to-measure volume and the vial yields exactly as many doses as before.
Why does this page not recommend a dose?
Because a dose is a clinical decision rather than a division. It depends on why someone is taking something, what else they take and how their kidneys and liver are working, none of which is knowable from a number typed into a box.
Where do the doses in the table come from?
Each is quoted from a specific paper indexed in Europe PMC, linked in the source column, and labelled with the kind of study it came from. The full evidence is on the Survodutide record.

What this calculator will not do

It will not take a body weight and return a milligram figure, and it will not tell you how often to draw. The table above is the published record, not a menu. A dose that appeared in a trial appeared under supervision, with monitoring, in people selected for that trial.

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